Causes: Primary Factors
Hypogonadism is characterized by underactive gonads and reduced hormone production. Factors are generally categorized into primary and secondary causes.
Primary Hypogonadism: Occurs when the gonads themselves (testes in men and ovaries in women) are unable to produce an adequate amount of hormones.
Genetic Conditions
Disorders like Klinefelter syndrome in males can lead to underdeveloped or nonfunctional gonads.
Trauma or Injury
Physical trauma, such as testicular injury, can impair hormone-producing capabilities permanently.
Infections
Infections like mumps can inflame and damage the testes, causing long-term production issues.
Clinical Treatments
Radiation therapy or chemotherapy can adversely affect the gonads and their cellular function.